| Transit agency | City | Vehicles operated directly | Website |
|---|---|---|---|
| Santee Wateree Regional Transportation Authority | Sumter | 43 | Official site |
| Pee Dee Regional Transportation Authority | Florence | 41 | Official site |
| Waccamaw Regional Transportation Authority | Conway | 31 | Official site |
| Lowcountry Regional Transportation Authority | Bluffton | 29 | Official site |
| Berkeley Charleston Dorchester RTMA | Moncks Corner | 28 | Official site |
| Spartanburg Regional Health Services, Inc. | Spartanburg | 28 | Official site |
| Greenville Transit Authority | Greenville | 23 | Official site |
| Williamsburg County | Kingstree | 19 | Official site |
| City of Clemson | Clemson | 17 | Official site |
| Fairfield County Transit System | Winnsboro | 16 | Official site |
| City of Rock Hill | Rock Hill | 8 | Official site |
| City of Spartanburg South Carolina | Spartanburg | 8 | Official site |
| Catawba Indian Nation | Rock Hill | 7 | Official site |
| City of Anderson | Anderson | 6 | Official site |
| Central Midlands Regional Transportation Authority | Columbia | 0 | Official site |
| Charleston Area Regional Transportation Authority | North Charleston | 0 | Official site |
| Lower Savannah COG | Aiken | 0 | Official site |
Largest first by vehicles operated directly, as each employer reports it to its federal registry.
Source: Federal Transit Administration, National Transit Database 2024 — Reporter Agency Information. Data captured September 30, 2026.